I used this one I had floating around in my bag and both the HDMI and USB3 ports worked on it. Had a call with Apple support and they said to try an Apple certified hub. I also replicated this issue on my M1 MacBook Air after updating to Monterey. I have tried different C ports on the MacMini and different hubs (I have 4). The HDMI port connected to my second screen is working on the hub but none of the USB3 ports are working at all.

My USB-C hub has issues with this update. Reddit user Flyersny81 relates their experience: Some of the problems even relate to Apple certified hubs. In other user reports surfacing online, the USB hubs fail to work at all. In some cases, users say the the USB 3.0 ports on their hub no longer work since upgrading to Monterey, while HDMI, USB-C, and other hub ports continue to work as expected. There have been several reports on Reddit, Apple's Developer Forums, and Apple's Support Communities about the issues.

Some Mac users who upgraded to macOS Monterey this week are experiencing problems getting USB hubs and other USB-based devices to work properly with their machines, based on scattered online reports.

Usb hub for macbook pro 2012